The fluticasone propionate-containing comparator used the same device and vehicle as DYMISTA and is not commerically marketed.1
First timepoint (30 minutes) at which Dymista significantly improved, and continued to improve, seasonal nasal allergy symptoms vs placebo in patients 12 years and older.1
Total nasal symptom score is calculated as the sum of the patients' scoring of the 4 individual nasal symptoms (rhinorrhea, congestion, sneezing, and itching) on a 0-to-3 categorical severity scale (0=absent, 1=mild, 2=moderate, 3=severe) averaged over a 14-day study period.1
FLONASE and DYMISTA may not be comparable in terms of efficacy and safety.
References: 1. Dymista [package insert]. Somerset, NJ: Meda Pharmaceuticals Inc., a Viatris Company; 2021. 2. Carr W, Bernstein J, Lieberman P, et al. A novel intranasal therapy of azelastine with fluticasone for the treatment of allergic rhinitis. J Allergy Clin Immunol. 2012;129(5):1282-1289.e10. 3. Flonase [package insert]. Research Triangle Park, NC: GlaxoSmithKline; 2020.